Cheap flights from Madrid, Spain to Santa Ana, CA

Travelers frequently search for route combinations, such as Madrid and London, Manchester, Dublin, Birmingham, Toronto, Edinburgh, Athens, Thessaloniki, Vancouver, Reykjavik, Glasgow, Bristol, Tallinn, Liverpool, Montreal, Copenhagen, Paris, Newcastle upon Tyne, Malta, Vienna.

Travelers frequently search for route combinations, such as Santa Ana and Austin, Toronto, Edmonton, London, Denver, Calgary, San Francisco, Portland, Seattle, Las Vegas, Reykjavik, Buffalo, Houston, Barcelona, Chennai, Charlotte, Birmingham, Fayetteville, Orlando, Dallas.

Madrid is mainly served by Adolfo Suárez Madrid–Barajas. But there are other airports nearby, including Torrejon Airport, Cuatro Vientos Airport.

The main airport in Madrid is Adolfo Suárez Madrid–Barajas. It is also served by Salamanca, Valladolid.

The main airport in Santa Ana is John Wayne. It is also served by Tijuana International, San Diego International, Ontario International, John Wayne, Palm Springs International, Hollywood Burbank, Long Beach, Santa Barbara Municipal, Meadows Field, Hawthorne Municipal.

Yes, it's possible to combine different modes of transport between Madrid and Santa Ana thanks to our Virtual Interlining technology. Making use of not only flights but also trains and buses between Madrid and Santa Ana can give rise to new adventures. Read more about how Virtual Interlining works on Kiwi.com Stories.

Virtual Interlining provides a revolutionary way of traveling. You can combine different modes of transport like flights, trains, and buses into one itinerary. And this often saves money. Thanks to the world's largest carrier database, the Kiwi.com search function enables anyone to mix and match different modes of transport easily.

Currently, you can fly between Madrid and Santa Ana with Spirit Airlines, Alaska Airlines, Iberia Airlines, TAP Portugal, Air Europa.

If you don’t have specific dates for your trip between Madrid and Santa Ana, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.