Cheap flights from Santa Ana to St. Louis from $161

Travelers frequently search for route combinations, such as Santa Ana and Las Vegas, Phoenix, Dallas, Denver, Seattle, Provo, Vancouver, Calgary, Oakland, Portland, Austin, Minneapolis, Sacramento, Cleveland, Chicago, Reno, Houston, Orlando, Eugene, Indianapolis.

Travelers frequently search for route combinations, such as St. Louis and Orlando, Las Vegas, Denver, San Diego, London, Los Angeles, Cancún, Fort Lauderdale, New York, Seattle, Mexico City, Charlotte, Sacramento, Boston, Minneapolis, Helsinki, Anchorage, Reno, Munich, Bogotá.

The main airport in Santa Ana is John Wayne. It is also served by Tijuana International, San Diego International, John Wayne, Ontario International, Palm Springs International, Hollywood Burbank, Long Beach, Santa Barbara Municipal, Imperial County, Hawthorne Municipal.

The main airport in St. Louis is St. Louis Lambert International. It is also served by St. Louis Lambert International, Abraham Lincoln Capital, Evansville Regional, General Wayne A. Downing Peoria International, Central Illinois Regional, MidAmerica St. Louis, Barkley Regional, Cape Girardeau Regional, Waynesville-St. Robert Regional, Quincy Regional.

Currently, you can fly between Santa Ana and St. Louis with Alaska Airlines, United Airlines.

If you don’t have specific dates for your trip between Santa Ana and St. Louis, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Santa Ana and St. Louis, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Santa Ana. The main one is John Wayne and other nearby airports include Tijuana International, San Diego International, John Wayne, Ontario International, Palm Springs International, Hollywood Burbank, Long Beach, Santa Barbara Municipal, Imperial County, Hawthorne Municipal

There are a number of airports in and around St. Louis. The main one is St. Louis Lambert International and other nearby airports include St. Louis Lambert International, Abraham Lincoln Capital, Evansville Regional, General Wayne A. Downing Peoria International, Central Illinois Regional, MidAmerica St. Louis, Barkley Regional, Cape Girardeau Regional, Waynesville-St. Robert Regional, Quincy Regional.