Cheap flights from Knoxville to Santo Domingo from $192

Travelers frequently search for route combinations, such as Knoxville and Las Vegas, New York, Boston, Denver, Seattle, Salt Lake City, Minneapolis, Fort Lauderdale, Guatemala City, Los Angeles, San Francisco, Orlando, Toronto, St. Louis, Portland, San Juan, Saint Thomas, Lisbon, Philadelphia, Punta Gorda.

Travelers frequently search for route combinations, such as Santo Domingo and Atlanta, Philadelphia, Fort Lauderdale, Orlando, Miami, San Juan, Dallas, New York, Minneapolis, Raleigh, Los Angeles, Tampa, Washington, D.C., Houston, Cleveland, Boston, Charlotte, San Francisco, Detroit, Medellín.

The main airport in Knoxville is McGhee Tyson. It is also served by Nashville International, McGhee Tyson, Asheville Regional, Greenville–Spartanburg International, Blue Grass, Chattanooga Metropolitan, Tri-Cities Regional.

The main airport in Santo Domingo is Las Américas International. It is also served by Punta Cana International, Cibao International, Gregorio Luperón International, La Romana International, Samaná El Catey International.

Currently, you can fly between Knoxville and Santo Domingo with Allegiant Air, United Airlines, JetBlue Airways, Spirit Airlines, Copa Airlines.

If you don’t have specific dates for your trip between Knoxville and Santo Domingo, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Knoxville and Santo Domingo, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Knoxville. The main one is McGhee Tyson and other nearby airports include Nashville International, McGhee Tyson, Asheville Regional, Greenville–Spartanburg International, Blue Grass, Chattanooga Metropolitan, Tri-Cities Regional

There are a number of airports in and around Santo Domingo. The main one is Las Américas International and other nearby airports include Punta Cana International, Cibao International, Gregorio Luperón International, La Romana International, Samaná El Catey International.