Cheap flights from Charleston to Sioux Falls from $250

Travelers frequently search for route combinations, such as Charleston and New York, Philadelphia, Tampa, Las Vegas, Orlando, Fort Myers, Los Angeles, San Juan, Denver, Cincinnati, Westchester County, New Orleans, San Diego, Fort Lauderdale, Phoenix, Boston, Pittsburgh, Dallas, Hartford, Detroit.

Travelers frequently search for route combinations, such as Sioux Falls and Denver, Los Angeles, Phoenix, Portland, Philadelphia, Nashville, Guatemala City, Tampa, Chicago, Santa Ana, Fort Lauderdale, San Francisco, San Diego, Guadalajara, Oakland, Jackson, Huntsville, San Antonio, Bozeman, Hartford.

The main airport in Charleston is Charleston International. It is also served by Charleston International, Myrtle Beach International, Savannah/Hilton Head International, Columbia Metropolitan, Hilton Head, Augusta Regional, Florence Regional, Brunswick Golden Isles.

The main airport in Sioux Falls is Sioux Falls Regional. It is also served by Sioux Falls Regional, Watertown Regional, Sioux Gateway.

Currently, you can fly between Charleston and Sioux Falls with United Airlines.

If you don’t have specific dates for your trip between Charleston and Sioux Falls, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Charleston and Sioux Falls, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Charleston. The main one is Charleston International and other nearby airports include Charleston International, Myrtle Beach International, Savannah/Hilton Head International, Columbia Metropolitan, Hilton Head, Augusta Regional, Florence Regional, Brunswick Golden Isles

There are a number of airports in and around Sioux Falls. The main one is Sioux Falls Regional and other nearby airports include Sioux Falls Regional, Watertown Regional, Sioux Gateway.