Cheap flights from Knoxville, TN to Des Moines, IA

Travelers frequently search for route combinations, such as Knoxville and London, Glasgow, Las Vegas, Boston, New York, Seattle, Denver, Salt Lake City, Minneapolis, Santo Domingo, San Juan, Dallas, Guatemala City, Los Angeles, Fresno, Fort Lauderdale, Houston, Phnom Penh, Orlando, San Francisco.

Travelers frequently search for route combinations, such as Des Moines and London, Los Angeles, Seattle, Denver, Nashville, Washington, D.C., Las Vegas, San Francisco, New York, Santa Ana, Boston, Portland, Orlando, Idaho Falls, Fort Lauderdale, San Diego, Mexico City, Salt Lake City, Guadalajara, Vancouver.

The main airport in Knoxville is McGhee Tyson. It is also served by Nashville International, McGhee Tyson, Asheville Regional, Greenville–Spartanburg International, Blue Grass, Chattanooga Metropolitan, Tri-Cities Regional.

The main airport in Des Moines is Des Moines International. It is also served by Des Moines International, Eppley Airfield, The Eastern Iowa, Kirksville Regional, Fort Dodge Regional, Mason City Municipal, Waterloo Regional, Southeast Iowa Regional, Sioux Gateway.

Currently, you can fly between Knoxville and Des Moines with United Airlines.

If you don’t have specific dates for your trip between Knoxville and Des Moines, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Knoxville and Des Moines, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Knoxville. The main one is McGhee Tyson and other nearby airports include Nashville International, McGhee Tyson, Asheville Regional, Greenville–Spartanburg International, Blue Grass, Chattanooga Metropolitan, Tri-Cities Regional

There are a number of airports in and around Des Moines. The main one is Des Moines International and other nearby airports include Des Moines International, Eppley Airfield, The Eastern Iowa, Kirksville Regional, Fort Dodge Regional, Mason City Municipal, Waterloo Regional, Southeast Iowa Regional, Sioux Gateway.