Cheap flights from Grand Cayman to San Francisco from £285

Travelers frequently search for route combinations, such as Grand Cayman and London, Edinburgh, Manchester, New York, Toronto, Panama, Manila, São Paulo, Washington, D.C., Barcelona, Atlanta, Dubai, Los Angeles, Kingston, Dublin, Cancún, Miami, Calgary, Venice, Vancouver.

Travelers frequently search for route combinations, such as San Francisco and London, New York, Los Angeles, Manchester, Calgary, Las Vegas, Phoenix, Toronto, Glasgow, Dallas, Chicago, Vancouver, Mexico City, Denver, San Diego, Minneapolis, Barcelona, Edinburgh, Paris, Salt Lake City.

The main airport in Grand Cayman is Owen Roberts International. It is also served by Owen Roberts International.

The main airport in San Francisco is San Francisco International. It is also served by San Francisco International, Sacramento International, San Jose International, Oakland International, Stockton Metropolitan, Charles M. Schulz–Sonoma County, Monterey Regional, Merced Regional.

Currently, you can fly between Grand Cayman and San Francisco with Cayman Airways, United Airlines, Frontier Airlines, Hawaiian Airlines, JetBlue Airways.

If you don’t have specific dates for your trip between Grand Cayman and San Francisco, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Grand Cayman and San Francisco, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Grand Cayman. The main one is Owen Roberts International and other nearby airports include Owen Roberts International

There are a number of airports in and around San Francisco. The main one is San Francisco International and other nearby airports include San Francisco International, Sacramento International, San Jose International, Oakland International, Stockton Metropolitan, Charles M. Schulz–Sonoma County, Monterey Regional, Merced Regional.